Archive | Diabetes Medication

New Type 2 Diabetes Drug

New medication for Diabetes – What is Ertugliflozin?

FDA Approves Ertugliflozin (Steglatro) For Treatment of Diabetes

Ertugliflozin, which will be sold under the brand name Steglatro, is a drug for treatment of Type 2 diabetes. Although more than 30 million Americans suffer from diabetes, about 90% of these patients have type 2 diabetes.

Ertugliflozin is a sodium-glucose co transporter (SGLT2) Inhibitor. It was developed by Merck &Co and Pfizer Inc. and it is classified under drugs commonly known as glifloins. Ertugliflozin recently won USFDA (United States Food and Drug Administration) for treatment of type  2 diabetes.

How does Ertugliflozin Work?

what drug is used to treat diabetes Being a sodium- glucose co-transporter (SGLT2) inhibitor, Ertugliflozin works by increasing secretion of glucose in the urine.

It mainly works  as part of two fixed-dose combinations which will constitute – dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin (Steglujan) ; available as five milligram of Ertugliflozin per a hundred milligram of sitagliptin and fifteen milligram per a hundred milligram of sitagliptin ) to be taken once daily and with metformin ( Segluromet ; two and half milligram of Ertugliflozin per five hundred milligram of metformin; two and a half milligram per a thousand milligrams) to be taken twice daily.

For the drug to get approval by the FDA two trials have been conducted; the VERTIS MET and VERTIS SITA trials. These trials show that Ertugliflozin has been able to meet its primary goals and is actually able to regulate blood sugar in the patients who participated in the study.

VERTIS MET was conducted over a twenty six week period. It evaluated the efficiency and safety of the drug in patients with Type 2 diabetes. The study was conducted by administering Ertugliflozin in combination with metformin in comparison to taking placebo and metformin alongside those taking just metformin.

Patients who took Ertugliflozin had lower blood sugar, had lost more weight and had low blood pressure.

In the VERTIS SITA trial, Ertugliflozin was administered in combination with sitagliptin in comparison to placebo with sitagliptin. Lower blood sugars were reported in Diabetes Type 2 patients who were taking Ertugliflozin.

Do the Drugs have any Side Effects?

Patients treated using drugs in Ertugliflozin’s class, sliflozin, have exhibited a few side effects. One of the effects reported is a condition known as KETOACIDOSIS. This is a serious life-threatening condition reported in both type 1 and type 2 diabetes patients. This is a condition that also requires urgent hospitalization.

If Ketoacidosis is detected, Ertugliflozin (Steglatro) should not be administered again. Patients should undergo keen examination before Steglatro is administered. Before initiating Steglatro risk factors such as pancreatic insulin deficiency from any cause, caloric restriction, and alcohol abuse should be taken into account.

Moreover, intravascular volume contraction has been reported in patients using Steglatro. It can also cause renal impairment. Acute kidney injury has also been reported in patients receiving sodium- glucose co-transporter (SGLT2) inhibitors. Factors that may predispose patients to acute kidney injury have to be considered before initiating steglatro. Ertugliflozin (Steglatro) should be discontinued immediately if acute kidney injury occurs and treatment should also be administered urgently.

Renal function should be evaluated before Ertugliflozin (Steglatro) is administered. This is because Ertugliflozin (Steglatro) increases serum creatinine and decreases eGFR which causes renal impairment.

Serious urinary tract infections including urosepsis and pyelonephritis have been reported in patient treated with Ertugliflozin (Steglatro) in clinical trials. Patients should be examined for urinary tract infection symptoms and should be treated urgently.

Even though Ertugliflozin (Steglatro) has not been linked to increased risk of lower limb amputation, factors that may predispose a patient to lower limb amputation should be considered and patients should be informed about it. This is because it has been observed that there is an increased risk of lower limb amputation in patients using SGLT2 inhibitors.

A lower dose of insulin or insulin secretagogue should be administered. This is because Ertugliflozin (Steglatro) may increase the risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. Other risks and side effects include genital mycotic infections.

European Medicines Agency is still reviewing Ertugliflozin (Steglatro). However, it’s expected to be available in the USA in early 2018.


Exenatide For Type 2 Diabetes

Exenatide is an injectable type 2 diabetes medication that is used along with exercise and diet in order to control the blood glucose level. It stimulates the pancreas to produce insulin efficiently when your blood glucose level is high. Exenatide also causes a significant decrease in appetite by slowing the emptying of your stomach. However, Exenatide should not be used to treat type 1 diabetes.

Using medication and making lifestyle changes such as exercising, dieting and quitting smoking will help you improve your health and manage your diabetes. This will also decrease the chances of having a stroke, heart attack and other diabetes related complications including nerve damage, kidney failure, gum disease, and eye problems. Your health care providers will advise you on the best way you can manage your diabetes.

When to Avoid Exenatide for Diabetes.

  • You should not use Exenatide if you are on dialysis or if you have severe kidney disease, diabetic ketoacidosis or if you have slowed digestion.
  • Exenetide should not be used together with Bydureon and short-acting or fast-acting insulin.

Is Exenatide Safe?  You should tell your health care provider if you have:

  • High triglycerides
  • A history of kidney transplant or kidney disease
  • A history of gall stones or pancreatitis
  • Digestion problems
  • A history of alcoholism

Birth control pills should be taken at least 1 hour before taking this medication.  You should also tell your doctors if you are pregnant, plan on becoming pregnant or become pregnant while using Exenatide.

Exenetide is not approved for use by people younger than 18 years.

How should I use Exenetide?

Exenatide immediate release, which is also known as Byetta, comes as a liquid (solution) in a prefilled injection pen for injecting subcutaneously.

Exenatide extended release (Bydureon) (long-acting) comes in powder form which is mixed with liquid in a prefilled injection pen or a vial to inject subcutaneously.

Exenatide immediate release (Byetta) should be injected twice per day within one hour before breakfast and dinner. It should not be injected before meals and your doses should be at least six hours apart. The doctor might start you on a low dosage and may switch you to a higher dosage of Exenatide if your blood glucose control does not improve after using the initial dosage for one month. The doctor might also adjust the dosage to make sure you have the best results.

Exenatide extended release solution should be injected once per week, on the same day each week without regard to meals. Use Exenatide exactly as instructed by your doctor.

Diabetics who use Exenatide immediate release need to purchase needles separately. Your doctor will tell you the needles you should use to inject the medication. Always look at your medication before injecting it. Exenatide should be as fluid, colorless and clear as water.  Do not use Exenatide in smaller or larger amounts or for longer than prescribed. Exenatide is injected under the skin and your doctor or pharmacist should show you how injections are used and how used syringes and needles should be disposed. Exenatide (Byetta) comes in a prefilled dosing pen with a user manual showing detailed instructions for using the injection pen.

Never share a cartridge, syringe or injection pen with anyone else since this can allow diseases or infections to pass from one person to the other.

Exenatide Dosage Information:

What should I do if I miss a dose?

If you’ve not yet eaten a meal, take the missed dose immediately. However, if it’s almost time for your next dose, or if you’ve already eaten, skip the dose you’ve missed.

What should I do if I overdose?

Seek medical attention immediately.  Exenatide overdose can cause nausea, vomiting and signs of low blood sugar such as feeling shaky, dizziness, headache irritability and hunger.

What are the side effects of Exenatide?

Stop using Exenatide and seek medical help if you have:

  • Low blood sugar: sweating, irritability, feeling anxious and shaky, dizziness, hunger and fast heart rate.
  • Kidney problems: Difficult or painful urination, little or no urination, swelling in your ankles or feet, short of breath or feeling tired.
  • Pancreatitis: Severe nausea and vomiting, severe pain in the upper stomach spreading to the back, or fast heart rate.
  • Feeling jittery and weak
  • Constipation, diarrhea, heart burn.

Seek emergency medical help if you notice any signs of allergic reaction to Exenatide; rapid heartbeats, hives, difficult breathing, feeling light headed, itching, and swelling of the face, throat, tongue or lips.

What drugs that can affect Exenatide?

Your doctor might recommend that you stop using:

  • Birth control pills
  • Antibiotics
  • Blood pressure medication
  • Pain medication
  • Oral diabetes medicine or insulin
  • Warfarin (Jantoven, Coumadin)

Exenatide might make it difficult for the body to absorb oral medication. Therefore, it is vital to tell your physician about all the medication you are taking including herbal products for Diabetes, vitamins and over-the-counter medicines.


Top 4 Diabetic Lotions to Help Increase Circulation.

Best Lotions for Diabetic Feet

Diabetes can cause deprivation of oxygen to your skin, leading to poor circulation that might lead to severe, chronic dryness, slow healing, redness, cracking and itching. This basically means that diabetics can get injured more easily and are more likely to get infections that take longer to heal. Here are some of the best lotions for diabetic feet that can help alleviate these diabetes complications:

  1. Neoteric Advanced Healing Cream

Neoteric advanced healing cream provides treatment for cracked, damaged and chronic dry skin. One of its main ingredients is TriOxygenc which helps infuse oxygen into your skin. This diabetic skin care cream is proven to speed healing and increase circulation by strengthening natural defenses of the skin. It provides instant soothing action by quickly restoring your skin to a healthier, smooth soft texture.

Main benefits

  • diabetic skin care lotionsEspecially great for feet and hands
  • Speeds healing by strengthening the natural defenses of the skin
  • Protects and restores chronic dry, damaged, cracked skin
  • Helps increase the skin’s natural collagen production and circulation
  • Promotes, healthier, stronger, more resilient skin
  • Provides therapeutic skin moisturization and protection
  • Non-greasy
  • Absorbs very easily

Best Cream for Diabetic Feet

Neoteric advanced healing cream provides exceptional skin care for people with all types of dry skin conditions including diabetes.

How to use

Apply as often as necessary or as directed by the healthcare expert or physician. Daily use is recommended to help maintain the skin’s soft, healthy appearance.

  1. Gold Bond Ultimate Hydrating Lotion – Diabetic Skin Care Lotions

With diabetes, your skin can become rough, cracked and uncomfortable. Gold bond ultimate hydrating lotion is specifically formulated for dry skin with hydralast and seven intensive moisturizers to hydrate and soothe the skin while adding a strong protective layer of moisture for up to 24 hours. Gold bond ultimate hydrating lotion is ideal for daily use and does not contain any harsh alpha hydroxyl acids that irritate the skin.

  • Foot Creams For Diabetic NeuropathyIdeal for all over body use
  • Contains aloe and essential vitamins that moisturize and nourish dry, flaky skin
  • Keeps the skin feeling and looking noticeably healthy
  • Hypoallergenic
  • Fragrance free
  • Exclusive formula that is dermatologist tested

Diabetic Cream for Feet

How to use

Apply Gold bond ultimate hydrating lotion liberally to rough, dry and problem skin areas to speed up moisturization.

  1. Eucerin Diabetics’ Skin Relief Body Lotion

Eucerin diabetics’ dry skin relief lotion is specifically designed to leave the skin feeling comfortable, hydrated and healthier all day long. This unique, non-greasy formula is enriched with alpha hydroxyl which repairs and exfoliates dry, flaky skin. Besides smoothening dry, rough skin, Eucerin diabetics’ skin relief body lotion noticeably improves overall skin condition and appearance just after one use! It is designed to repair, enhance and protect your skin, giving you the confidence that comes from healthy-looking and radiant skin.


  • Diabetic Lotions to Help Increase CirculationThe alpha hydroxyl formula smoothens rough, dry skin after just one use
  • Fast absorbing and lightweight
  • Fragrance free
  • Clinically proven formulation that provides 24-hour moisture
  • Paraben free
  • Dermatologist recommended brand

How to use

Apply liberally over rough, dry skin every day or as recommended by the physician. Apply immediately after showering or bathing for best results.

  1. DiabetAid Pain and Tingling Relief Lotion

Diabetes can cause two main problems that hurt your legs and feet. One complication is damage to the nerves which leads to an infection or a sore. The other problem is blood flow which can make it hard for an infection or sore to heal. However, if you check for sores or cut sand wash your feet and hands with mild soap, chances of infections are greatly reduced. Sometimes you may also feel a tingling sensation in your hands and feet. Applying DiabetAid pain and Tingling Relief Lotion will relieve those uncomfortable sensations.


  • Lotion That Helps CirculationSoothing relief for uncomfortable tingling in the feet and hands
  • Contains 4 essential moisturizers to relieve dry, rough skin
  • Does not contain any ingredients that are considered harmful or dangerous to diabetics.

How to use

Apply to affected areas daily but you should avoid applying more than 4 times per day. Children under 2 years should consult a doctor for directions and recommendations.


Latest News on Invokana for Diabetes.

Invokana for Diabetes

Invokana for Diabetes

Are you interested in the latest developments on Invokana for diabetes? Today the European Commission (EC) announced that they have approved Invokana (canagliflozin) tablets in the European Union for helping to maintain glycemic control in adult type 2 diabetes sufferers.

Invokana is a prescription medication designed for diabetics to use in conjunction with a well monitored diabetic diet and exercise plan, to lower blood sugar levels. The way Invokana works is it blocks the re absorption of glucose by the kidney, which then increases glucose excretion, hence lowers your blood sugar levels.

  When NOT to take Invokana for Diabetes

  • Invokana should not be taken by type 1 sufferers, also by
  • diabetes patients on dialysis,
  • those who have severe or late stage of renal disease, or
  • Diabetic Ketoacidosis (elevated level of ketones in the urine or blood)

Side Effects of Invokana

It is important to understand that Invokana may cause side effects in some diabetics.  These are mostly apparent in the first three months of starting treatment and may include:

  •         Dehydration
  •         Dizziness or lightheadedness
  •         Weakness
  •         Yeast infections in both men and women.
  •         Urinary tract infections

It is always vital you consult with your doctor or diabetes management team, before you start with any new medications. Also be sure to advise what other medications you are taking, as some medications may affect the way Invokana works and vice versa, some of these include:

  •  Diuretics (water pills)
  •  Rifampin (Tuberculosis medication)
  •  Phenobarbital or Phenytoin (seizures)
  •  Ritonavir ( HIV infection treatment)
  •  Digoxin (Heart problems)

Before you take Type 2 Diabetes Medication – first Tell your Doctor:

  •       If you’re pregnant
  •       If you are breastfeeding
  •       If you are having any form of liver of kidney problems.
  •       If you are having allergic reactions to the drug.
  •       What sort of diabetic diet plan you are following, ie low in salt etc..

So combined with a well managed diabetes diet plan,  regular exercise and close monitoring from your physician, Invokana for diabetes, is one step closer to controlling your blood sugar levels and living a normal, healthy life!


Type II diabetic medications

Type II Diabetes MedicationsType II diabetic medications are in abundance and can be found in many different types and kinds as well as styles. There are these types of medications that can be found in prescription form or there is medication that can be found naturally and at modern day health food stores.

Some of the most common type II diabetic medications are Glucophage which can be used before a person has full blown diabetes in order to get their weight down and blood sugar levels as a precautionary measure or during their diagnosis of diabetes in order to help keep their blood sugar levels down.

Novolog and Humalog are two widely known and used diabetic medications because they come in insulin form which means that they are normally injected through a syringe or needle as needed. Many times with a diabetic they will need to monitor their blood sugar levels and amounts several times throughout the day such as first thing in the morning before they eat, around lunchtime and then again at supper or bedtime, during this time if their blood glucose levels are too high or too low they may need to inject themselves with amounts of novolog or humalog in order to control that number or reading.

With so many medications out there for diabetics often times it may be hard to understand what all the different medications are and how to use them properly but with the guidance of your family provider or physician they can walk you through the whole process and help you so that you can get the right treatment that you need in order to properly maintain and treat your type II diabetes. Type II diabetic medications come in all shapes, sizes, forms and kinds and getting knowledge about them is one of the most important things that you can do for yourself and your health!


Diabetes financial help

Diabetes Financial HelpHaving diabetes can get rather costly that is why so many diabetics start looking for diabetes financial help for assistance so that they can help properly manage and maintain their diabetes and get all the help and medications that they need in order to do so.

Diabetes can get rather costly with all of the medications, blood glucose meters, testing supplies, diets, doctor visits and everything else that a diabetic may have to have. With this day and time so many more people are finding themselves getting laid off from their job, losing their insurance and so they are faced with the daunting tasks of deciding between their medications and food on their table that’s why more and more people are looking for financial help such as diabetes financial assistance in which they can get their diabetic stability and help keep their diabetes maintained and properly managed.

Diabetes financial help is everywhere, one of the best places to find financial assistance is through a Diabetic Health Insurance or by talking to your local healthcare provider who can point you in several different places or the one that best suits your needs. A lot of times your healthcare provider can look at your specific needs and which will help point you in the right direction.

There are many different companies out there that can help you and your diabetes needs from helping out financially with medications, diabetic supplies or by helping you get to and from doctor’s offices and appointments. Diabetes financial help can range from county to county and situation to situation so it is best to weigh all the pros and cons to see which one will work best for you. There is no harm in talking to someone and let them see what they can do for you. With so many firms out there catering to help out diabetics, why not see one today?


Who discovered diabetes?

who discovered diabetes

who discovered diabetes

Who discovered diabetes? Historical records show that diabetes has been recognized by the Egyptians way back to 1500 B.C. The ancient Greek physician named Aretaeus of Cappadocia coined the term ‘diabetes.’ Sometime in the 1600s, the urine of patients who suffered from this particular type of disease was described as sweet. Later on, the term ‘mellitus’ was added by English doctor Thomas Willis in 1675. German scientist Oskar Minkowski and German physician Joseph von Mering successfully described the connection between the pancreas and diabetes.

When it comes to diabetes it has been said that diabetes has been dated back even into the Ice age or caveman time. Diabetes, which is referred to as diabetes mellitus, is a medical condition that affects millions of people from all parts of the world. Common symptoms of this disease include increased thirst as well as frequent urination. Diabetes affects many million each and every year and even though we often spend so much time learning about how to treat diabetes, the side effects, symptoms and what the disease is and how to treat it we often forget to learn about who discovered diabetes?

Who discovered diabetes and who discovered other diseases, cures and everything else about it can be very important to knowledge to know. A lot of times we know what the disease or illness is about and how to treat it or keep it maintained but we often times don’t know why it was called what it was or who first discovered it which can also be very important knowledge.

Diabetes can cause many other diseases as well if left untreated such as peripheral neuropathy, vascular diseases and problems, kidney failure, serious infections, strokes and even lead to death. So the next time you think that you know all there is to know about a disease, learn who discovered it such as who discovered diabetes you may be surprised!


Diabetic medical alert jewelry

diabetic medical alert jewelry

diabetic medical alert jewelry

Are you a diabetic or know someone that is? Diabetics need to signify or signal to others at all times that they are in fact a diabetic because of their medical condition and when you are a diabetic it isn’t anything to play with or mess with. Thus, giving a new reason to wear diabetic medical alert jewelry.

Diabetic medical alert jewelry is a great way to let people know at all times that you are a diabetic and people around you should be aware. Diabetic medical jewelry comes in all sizes, styles and colors so that you can alert people around you of your medical condition without feeling like you have a large red flag on your screaming, “I am a diabetic.”

For many diabetics, they don’t want to show the whole world that they are a diabetic but they must also realize that when you are a diabetic certain precautionary levels should be taken in case something happens to you beyond your control.

Diabetic medical alert jewelry can be found in all different styles such as bracelets which can be wore and so fashionable that most don’t even realize it states that you are a diabetic. There are also diabetic necklaces, charms, anklets and charms that can be placed on your watches or chains so that it can be discrete all at the same time and fashionable.

Diabetic medical alert jewelry needs to be wore on diabetics because if you were to get into a wreck, pass out, fall or any other type of emergency the medical staff would need to know right away that you are a diabetic in order to treat you properly and safely. Giving a patient who is a diabetic the wrong kind of medication can be detrimental to their health and hurt them more than do them good.


Type II diabetes medication

type ii diabetes medication

type ii diabetes medication

The main type II diabetes medication is that of insulin which more than likely when you know a type II diabetic you will hear them say that the only way that they can get a grasp on their diabetes and maintain them is by using insulin in compliance with diabetes and exercise so that their health and diet can be maintained and their diabetes can be manageable.

Type II diabetes medication comes in many different types and forms such as insulin being the most popular, Glucotrol XL and Glucophage are two other popular forms, both being oral medications which generally come in pill form. Glucotrol XL and Glucophage are both highly known diabetes medications and widely as treating and helping maintain type II diabetes medication.

These type II diabetes medications contain metaformin which allows your body to be able to balance the insulin that it takes in and is able to produce so that you can have it all balanced in no time. Metaformin medications are more likely to be used with diabetics and people who have kidney problems because the Metaformin is easier on your system versus the other diabetic medications.

A lot of times when someone is starting to have diabetic symptoms or showing signs of diabetes the doctor may put you on some type of Metaformin such as Glucotrol XL, Glucophage or insulin as a precautionary measure so that possibly you can control your diabetes with medication without having to go to insulin as a last resort.

Type II diabetes medication can come in liquid forms, pill forms, forms in which you have to inject just to name a few. Type II diabetes doesn’t mean the end of the world nor does it automatically mean that you have to rely on insulin for the rest of your life there are other types of medications that can be tried first.